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Methylene Blue 1% Solution (Pharmaceutical Grade)

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Contents: 60ml

Pharmaceutical grade methylene blue 1% solution in purified water. Laboratory tested and UV-protected packaging with glass pipette for maximum stability and purity.

Pharmaceutical grade — USP-grade methylene blue without impurities
UV-protected packaging — with precision glass pipette for accurate dosing
Laboratory tested in Germany — certificate of analysis for maximum assurance
No artificial additives — only purified water and methylene blue
60ml supply — sufficient for long-term research
Contents: 60ml
Free shipping from €50Independently lab testedOrdered before 6PM = shipped today

Benefits

Pharmaceutical grade methylene blue 1% solution in purified water. Laboratory tested in Germany with certificate of analysis.

  • ✓ Laboratory tested
  • ✓ UV Protected Packaging
  • ✓ No Additives

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Important Information

Critical Drug Interactions

Serotonergic medications: Do NOT combine methylene blue with SSRIs (fluoxetine, sertraline, paroxetine, citalopram, escitalopram), SNRIs (venlafaxine, duloxetine), MAO inhibitors, triptans, or St. John's Wort. The combination may cause serotonin syndrome — a potentially life-threatening condition. Symptoms include: agitation, confusion, rapid heart rate, high blood pressure, dilated pupils, muscle rigidity, and hyperthermia. Seek immediate medical attention if symptoms occur.

G6PD Deficiency

Do NOT use if you have glucose-6-phosphate dehydrogenase (G6PD) deficiency. Methylene blue may cause haemolytic anaemia in individuals with this condition. If you are unsure about your G6PD status, consult your physician before use.

General Warnings

  • This product is not a food supplement and is not intended for consumption as such (Novel Food Regulation EU 2015/2283).
  • For research and laboratory purposes only.
  • Keep out of reach of children.
  • Store in a cool, dark place. UV-protected packaging preserves stability.
  • May cause temporary blue discoloration of skin, urine, and mucous membranes.
  • Consult your physician before use if you are pregnant, nursing, or taking any medication.
  • Do not use if you have renal insufficiency.
Benefits
MB

Pharmaceutical grade

USP-grade methylene blue without impurities such as heavy metals. Laboratory tested with certificate of analysis.

UV

UV-protected packaging

Dark glass bottle with precision glass pipette protects against light degradation and ensures accurate dosing.

1%

Exact concentration

Precisely 1% methylene blue in purified water. No artificial colors, preservatives or other additives.

DE

Laboratory tested in Germany

Each batch is tested for purity, concentration and microbial safety by an independent German laboratory.

60

Sufficient supply

60ml content provides ample supply for research purposes. Glass pipette enables precise dosing.

WHO

WHO Essential Medicine

Methylene blue is on the WHO Essential Medicines List and is one of the oldest synthetic compounds in medicine (1876).

Legal notice: According to the provisions of the Novel Food Regulation of the European Union, methylene blue is not considered a food and may not be marketed as such.

Research background

Methylene blue was discovered in 1876 as a textile dye, but medical applications were soon discovered. The molecule can function as an alternative electron carrier in the mitochondrial electron transport chain.

Research areas include mitochondrial function, cellular energy production, neuroprotection and antimicrobial properties. Important: at low doses it works as an antioxidant, at high doses as a pro-oxidant (hormesis curve).

Ingredients & Quality
IngredientPer 60ml
Methylene blue600mg (1%)
Purified water59.4ml

Complete ingredient list

Purified water, methylene blue 1%

No artificial additivesNo preservativesUSP pharmaceutical gradeLaboratory tested
Usage & Dosage

Important information

Warning: Not suitable for consumption. Not a food supplement. Not a medicine.

Methylene blue stains strongly. Avoid contact with textiles and surfaces.

Do not combine with SSRIs, SNRIs, MAO inhibitors or other serotonergic medication — risk of serotonin syndrome.

Storage instructions

• Store in a cool, dry place away from direct sunlight

• Keep out of reach of children

• Keep well sealed after use

• Shelf life up to 2 years from production date

Shipping

Netherlands & Belgium: 1-2 working days

Germany, France & Rest EU: 1-4 working days

Free shipping from €50 • Safely packed in UV-protective box

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Money back guarantee • No hassle • Just return

This product falls under the Novel Food Regulation (EU 2015/2283) and is not intended as food or supplement.

Why NOTFORTOMORROW?
FeatureNOTFORTOMORROWStandard brand
Pharmaceutical grade (USP-grade)
Laboratory tested with certificate
UV-protected glass packaging
Precision glass pipette included
No artificial additives
30-day money-back guarantee

Our quality promise

We only deliver products of the highest quality. Each batch is tested by independent laboratories in Germany. Transparency, purity and reliability are central to everything we do.

Frequently Asked Questions

What exactly is methylene blue?

Methylene blue (methylthioninium chloride) is one of the oldest synthetic compounds in medicine, discovered in 1876. It is on the WHO Essential Medicines List for treatment of methemoglobinemia. However, this product is not intended as a medicine or supplement.

Why pharmaceutical grade?

Industrial grade methylene blue (for textile or laboratory use) may contain impurities such as heavy metals. Pharmaceutical grade (USP-grade) undergoes strict purification tests and is free from harmful byproducts.

Why does urine/stool turn blue-green?

This is a normal and harmless side effect of methylene blue. The color change is temporary and disappears when the body has excreted the substance. It is not a sign of a problem.

Can I combine this with medication?

Do not combine with SSRIs, SNRIs, MAO inhibitors or other serotonergic medication due to risk of serotonin syndrome. Also do not use with G6PD deficiency (favism). Always consult a doctor when taking medication.

Smart combinations for mitochondrial support

For optimal mitochondrial function, other compounds are also interesting: CoQ10 (Ubiquinol) 100-200mg for complex III support, PQQ 10-20mg for mitochondrial biogenesis, NAD+ precursors (NMN/NR) for cellular energy, and Alpha-lipoic acid 300-600mg as universal antioxidant.

How do I store this best?

Store in the original UV-protected glass bottle, in a cool and dry place away from direct sunlight. Always seal well after use. With proper storage, the product maintains its quality for 2 years.

The Science

What does science say about methylene blue?

Methylene blue (MB) was first synthesised in 1876 and is one of the oldest synthetic compounds studied in medical science. Originally used as a textile dye, researchers quickly discovered its remarkable biological properties.

Mitochondrial function & cellular energy

Research published in Progress in Neurobiology demonstrated that methylene blue functions as an alternative electron carrier in the mitochondrial electron transport chain (ETC). This means MB can support ATP production — the cell's primary energy source — even when certain complexes in the chain are blocked.

Source: Rojas et al. (2012) — Progress in Neurobiology, 96(1), 32-45. DOI: 10.1016/j.pneurobio.2011.10.007

Functional brain connectivity

A study published in Brain Imaging and Behavior examined the effects of low-dose methylene blue on brain activity in healthy subjects. Using fMRI scans, the researchers showed that MB improved functional connectivity in brain regions involved in sustained attention and short-term memory.

Source: Rodriguez et al. (2016) — Brain Imaging and Behavior, 11(3), 640-648. DOI: 10.1007/s11682-016-9541-6

Cellular protection & oxidative stress

Published in the Journal of Biological Chemistry, this research demonstrated that methylene blue can act as an alternative electron route when standard mitochondrial complexes (Complex I and III) are blocked. This restores cellular respiration and reduces the production of reactive oxygen species (ROS) — molecules that can cause cell damage.

Source: Wen et al. (2011) — Journal of Biological Chemistry, 286(18), 16504-16515. DOI: 10.1074/jbc.M110.208447

Pharmaceutical quality

NOTFORTOMORROW exclusively uses pharmaceutical-grade methylene blue (USP grade, ≥98% purity). Industrial or laboratory-grade methylene blue may contain contaminants such as heavy metals and is not suitable for human use. Every batch is independently tested by an accredited laboratory.

Disclaimer: The information above is based on scientific research and is for educational purposes only. Methylene blue currently has no approval as a food supplement under the EU Novel Food Regulation (EU 2015/2283). This product is offered as research reference material.